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KMID : 0882420140860050651
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Korean Journal of Medicine
2014 Volume.86 No. 5 p.651 ~ p.654
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Splenic Infarction as the Initial Manifestation of Antiphospholipid Syndrome in a Systemic Lupus Erythematosus Patient
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Jeong Hye-Yun
Kang San-Ha
Song Ji-Hyun
Shin Sun-Young
Min Daniel
Han Kyu-Hyun
Choi Jin-Jung
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Abstract
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Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipid antibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complication of arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of left upper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhage and splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-day duration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenic infarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndrome that presented as a splenic infarction in a SLE patient.
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KEYWORD
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Lupus erythematosus, Systemic, Antiphospholipid syndrome, Splenic infarction
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